Potassium Carbonate → HCID 18918799, compound

Participants

Reaction Steps

To a solution of 6-isopropyl-7-methylimidazo[1,2-a]pyrimidin-5-one (0.400 g, 2.23 mmol) and 4-(4-chlorobenzoyl) benzyl bromide (0.762 g, 2.46 mmol) in DMF (15.0 ml) was added potassium carbonate (0.600 g, 4.50 mmol) and the mixture was stirred at room temperature overnight. The solvent was then distilled off and the residue was purified by silica gel column chromatography (methylene chloride: acetone=20:1) to provide a colorless amorphous solid.

Provenance & Evidence