Aniline → HCID 53742001, compound

HRID 1291583Notes

Reaction equation

HRID 1291583 reaction equation
[CH:1]([C:3]1[S:7][C:6]([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)=[CH:5][CH:4]=1)=O.[NH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C1C=CC=CC=1>[C:14]1([N:13]=[C:1]=[C:3]2[S:7][C:6]([C:8]3[S:9][CH:10]=[CH:11][CH:12]=3)=[CH:5][CH2:4]2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 6115AnilineHCID 364428[2,2'-Bithiophene]-5-carboxaldehyde

Product 1

HCID 53742001HCID 53742001, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Conditions

Temperature
85 °C

Procedure

5.0 g of 5-formyl-2,2'-bithiophene was dissolved in 45 ml of benzene. 2.4 ml of aniline was added and refluxed for 24 hours at 85° C. 6.9 g of crude product was obtained after removal of solvent under reduced pressure and the purer product could be obtained by recrystallization with ethanol.

Workup

  1. custom6.9 g of crude product was obtained
  2. customafter removal of solvent under reduced pressure
  3. customthe purer product could be obtained by recrystallization with ethanol

Sources & evidence

ORD record
ord-7e77fcebfd9642cf9eba90f3293b40fc
Source dataset
uspto-grants-1998_05
Patent number
US05753692

Reaction notes

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