Gamma-Butyrolactone → HCID 18658490, compound

HRID 1291686Notes

Reaction equation

HRID 1291686 reaction equation
[C:1]1(=[O:6])[O:5][CH2:4][CH2:3][CH2:2]1.[CH3:7][NH:8][CH2:9][C@@H:10]([C@H:12]([C@@H:14]([C@@H:16]([CH2:18][OH:19])[OH:17])[OH:15])[OH:13])[OH:11]>CO>[OH:5][CH2:4][CH2:3][CH2:2][C:1]([N:8]([CH2:9][C@@H:10]([C@H:12]([C@@H:14]([C@@H:16]([CH2:18][OH:19])[OH:17])[OH:15])[OH:13])[OH:11])[CH3:7])=[O:6]

Participants

4

Reactant 2

HCID 7302Gamma-ButyrolactoneHCID 8567N-Methyl-D-glucamine

Product 1

HCID 18658490HCID 18658490, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

500 ml (565 g, 6.56 mol) of gamma-butyrolactone are placed in 2.0 l of methanol. 1.28 kg (6.56 mol) of methylglucamine are added to the solution obtained. The mixture is then refluxed for 16 hours. The solution obtained is evaporated to dryness. The colourless syrup so initially obtained crystallises into a white solid after a few days at room temperature. (Melting point 78°-79° C.)

Workup

  1. customobtained
  2. temperatureThe mixture is then refluxed for 16 hours
  3. customThe solution obtained
  4. customis evaporated to dryness
  5. customThe colourless syrup so initially obtained
  6. customcrystallises into a white solid after a few days at room temperature

Sources & evidence

ORD record
ord-4cae1be4f5bb4f60a721b3bed446eb2e
Source dataset
uspto-grants-1998_05
Patent number
US05753708

Reaction notes

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