Water → HCID 15343903, compound

Participants

Reaction Steps

2 mmol of methyl 4-fluoro-3-trifluoromethylbenzoate, 2 mmol of 3-hydroxypyridine and 4 mmol of K2CO3 were stirred at 110° C. for 1.5 h in 15 ml of DMF (anhydrous). The mixture was then poured onto 100 ml of water and extracted 3 times using 50 ml of EA each time. It was dried over Na2SO4, the solvent was removed in vacuo and the product was reacted further without further purification.

Provenance & Evidence