Acetic Anhydride → HCID 54190602, compound

Participants

Reaction Steps

1 ,2-di(p-bromophenyl)-hydroxyethane (17.8 g, 0.05 mol), potassium iodide (165 g), copper (I) iodide (95 g) and hexamethylphosphoramide (200 mL) was stirred at 150-160° C. for 48 h and then cooled. Work-up was as described in Example IV to provide a light yellow solid (10 g), which was the expected 1,2-di(p-iodophenyl)-1-hydroxyethane. A portion of this compound (7.2 g, 0.016 mol), acetic anhydride (16 mL), pyridine (16 mL) were heated at 60° C. for 30 min, followed by standing for 2 days. The resulting solution was worked up as in Example IlIl to provide an oil which solidified upon standing. The solid was crystallized from hexanes to provide the title compound as a light yellow solid (4.3 g).

Provenance & Evidence