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HRID1292047

反应详情

EQUATION

反应方程式

HRID 1292047 的结构方程式

REACTANTS

反应物

2
结构：ClCCl
HCID6344

Dichloromethane

CH2Cl2

结构：COC(=O)c1c(C(F)(F)F)ccnc1C
HCID18914102

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nccc(C(F)(F)F)c1CO
HCID18914110

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Methyl 2-methyl-4-trifluoromethylnicotinate was reduced using the procedure as given in step 1 of Example 3. 3-Hydroxymethyl-2-methyl-4-trifluoromethylpyridine was obtained as a pale yellow waxy solid(TLC Rf = 0.31 (97:3 CH2Cl2 :MeOH)).