Methanol → HCID 18914100, compound

HRID 1292049Notes

Reaction equation

[Cl:1][CH2:2][C:3]1[C:4]([CH3:13])=[N:5][CH:6]=[CH:7][C:8]=1[C:9]([F:12])([F:11])[F:10].C(Cl)Cl.C[OH:18]>>[Cl:1][CH2:2][C:3]1[C:4]([CH3:13])=[N+:5]([O-:18])[CH:6]=[CH:7][C:8]=1[C:9]([F:12])([F:10])[F:11]

Participants

Reactant 3

HCID 887Methanol

HCID 6344Dichloromethane

HCID 18914101HCID 18914101, compound

Product 1

HCID 18914100HCID 18914100, compound

Procedure

3-Chloromethyl-2-methyl-4-trifluoromethyl -pyridine from step 2 above was oxidized using the procedure as given in step 3 of Example 3. 3-Chloromethyl-2-methyl-4-trifluoromethyl-pyridine-N-oxide was obtained as a white solid (TLC Rf = 0.21 (97:3 CH2Cl2 :MeOH)).

Sources & evidence

ORD record: ord-1fc1d4c7d11b46728cbbb6ee17e530fe
Source dataset: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05756497

Reaction notes

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