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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1292116Generated: November 1, 2026

4-(Bromomethyl)-1,2-difluorobenzene → HCID 18914212, compound

https://huagongshe.com/reaction/1292116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)-1,2-difluorobenzeneHCID 581436—
ReactantHCID 18914218HCID 18914218—
ProductHCID 18914212HCID 1891421296.5%

Reaction Steps

As in the case of Example 18, 1-(4-hydroxy-3-isobutylbenzoyl)-4-isobutylpiperazine (1.24 g) was benzylated with 3,4-difluorobenzyl bromide (1.60 g), thereby yielding 1.67 g of the aimed compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05756505
Source datasetuspto-grants-1998_05
ORD IDord-f442a79374e1436e9f42d509556c73fc
Source noteuspto-grants-1998_05