Methyl iodide → HCID 18914285, compound

HRID 1292118Notes

Reaction equation

HRID 1292118 reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][C:11](=[O:14])[CH:10]([CH3:15])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:16][I:17]>CC(C)=O>[I-:17].[CH3:16][N+:8]1([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:13][CH2:12][C:11](=[O:14])[CH:10]([CH3:15])[CH2:9]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 5609651-Benzyl-3-methyl-4-piperidone

Product 1

HCID 18914285HCID 18914285, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 10 g of 1-benzyl-3-methyl-4-oxopiperidine and 8 mL of methyl iodide in 100 mL of acetone was stirred at 25° to 30° C. for 6 days then concentrated under reduced pressure to dryness. Drying under vacuum overnight gave 17 g of 1-methyl-1-benzyl-3-methyl-4-oxopiperidinium iodide as a beige foam.

Workup

  1. concentrationthen concentrated under reduced pressure to dryness
  2. customDrying under vacuum overnight

Sources & evidence

ORD record
ord-7007cdf93b7e44f98fcd70ef6fae3d39
Source dataset
uspto-grants-1998_05
Patent number
US05756508

Reaction notes

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