反应详情

温度

40 °C

To 3-(4-carboxymethylbenzyloxy)benzamide (Compound NU1041) (0.03 g; 0.1 mmol) was added methanol (3 ml) and aqueous sodium hydroxide (1M; 3 ml). This was warmed to 40° C., and the reaction monitored. Upon the disappearance of the starting material the solution was acidified (aqueous HCl dropwise), and extracted into ethyl acetate (3×30 ml). The organics were pooled, dried over magnesium sulphate, and the solvent removed under reduced pressure. This yielded a white crystalline solid.

1. extractionextracted into ethyl acetate (3×30 ml)
2. dry with materialdried over magnesium sulphate
3. customthe solvent removed under reduced pressure
4. customThis yielded a white crystalline solid