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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1292978Generated: October 30, 2026

4-Methyl-2-oxo-4-phenylpentanoic acid ethyl ester → 2,4-Diphenyl-2-hydroxy-4-methylpentanoic Acid-ethyl Ester

https://huagongshe.com/reaction/1292978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyl-2-oxo-4-phenylpentanoic acid ethyl esterHCID 11333779—
ReactantHCID 178420681HCID 178420681—
Product2,4-Diphenyl-2-hydroxy-4-methylpentanoic Acid-ethyl EsterHCID 69423584—

Reaction Steps

Analogously to Example 1, 1.0 g of 4-methyl-4-phenyl-2-oxopentanoic acid-ethyl ester is converted with 2.14 ml of a 2 M phenylmagnesium chloride-THF solution into 980 mg of product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238707B2
Source datasetuspto-grants-2007_07
ORD IDord-4a17ea35d5444480836501f0eb3de796
Source noteuspto-grants-2007_07