Dimethyl Sulfoxide → HCID 86599001, compound

HRID 1292979Notes

Reaction equation

HRID 1292979 reaction equation
[C:1]1([C:7]([OH:20])([CH2:10][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([CH3:13])[CH3:12])[CH2:8][OH:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CS(C)=O>C(N(CC)CC)C>[C:1]1([C:7]([OH:20])([CH2:10][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([CH3:13])[CH3:12])[CH:8]=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 679Dimethyl SulfoxideHCID 69423545HCID 69423545, compound

Product 1

HCID 86599001HCID 86599001, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Analogously to Example 1, 445 mg of 2,4-diphenyl-4-methyl-1,2-pentanediol is converted with 1.02 g of pyridine-sulfur trioxide complex, 5.85 ml of DMSO and 1.16 ml of triethylamine into 390 mg of aldehyde.

Sources & evidence

ORD record
ord-888ae14cd868474fbfb8ef2139978cfe
Source dataset
uspto-grants-2007_07
Patent number
US07238707B2

Reaction notes

Loading…