反应详情

To a mixture of 3-chlorosulfonyl-1-dimethylcarbamoyl-1H-1,2,4-triazole (240 mg) and ethyl acetate (2 ml) was added pyridine (0.2 ml) on a water bath at room temperature. At this temperature the mixture was stirred for 1 hour. The reaction solution was washed with water, followed by saturated aqueous sodium chloride solution, and concentrated. The residue was subjected to a silica-gel column chromatography with 20 to 30% (20% 2-propanol/ethyl acetate)/hexane to yield the title compound (29 mg).

1. washThe reaction solution was washed with water
2. concentrationconcentrated