HCID 57572271, compound → Methyl 4-[({[5-fluoro-2-(4-fluorophenoxy)pyridin-3-yl]carbonyl}amino)methyl]-2-methylbenzoate

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 3 of Example 1 from 5-fluoro-2-(4-fluorophenoxy)nicotinic acid (step 3 of Example 1) and methyl 4-(aminomethyl)-2-methylbenzoate: 1H-NMR (CDCl3) δ 8.38 (1H, dd, J=8.1, 3.1 Hz), 8.30–8.24 (1H, m), 8.05 (1H, d, J=3.1 Hz), 7.88 (1H, d, J=8.1 Hz), 7.26–7.08 (6H, m), 4.71 (2H, d, J=5.9 Hz), 3.90 (3H, s), 3.87 (3H, s); MS (ESI) m/z 413 (M+H)+, 411 (M−H)−.

Provenance & Evidence