3-Chlorophenol → Methyl 5-chloro-2-(3-chlorophenoxy)benzoate

HRID 1293223Notes

Reaction equation

HRID 1293223 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5](F)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[Cl:13][C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][C:16]2[CH:17]=[CH:18][CH:19]=[C:14]([Cl:13])[CH:15]=2)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8]

Participants

3

Reactant 2

HCID 79333-ChlorophenolHCID 21525433Methyl 5-chloro-2-fluorobenzoate

Product 1

HCID 57572336Methyl 5-chloro-2-(3-chlorophenoxy)benzoate

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 5-chloro-2-fluorobenzoate and 3-chlorophenol: 1H-NMR (CDCl3) δ 7.92 (1H, d, J=2.8 Hz), 7.46 (1H, dd, J=8.8, 2.8 Hz), 7.25–6.80 (5H, m), 3.81 (3H, s).

Sources & evidence

ORD record
ord-1bcb41be79524188aa0972a63a632668
Source dataset
uspto-grants-2007_07
Patent number
US07238714B2

Reaction notes

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