Phenol → HCID 69417840, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from methyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 48) and phenol: 1H-NMR (CDCl3) δ 8.54 (1H, d, J=2.8 Hz), 8.21 (1H, d, J=7.3 Hz), 8.13 (1H, d, J=2.6 Hz), 8.00 (2H, dd, J=6.6, 1.8 Hz), 7.50–7.41 (4H, m), 7.34–7.29 (1H, m), 7.20–7.15 (2H, m), 5.42–5.33 (1H, m), 3.89 (3H, s), 1.61 (3H, d, J=7.0 Hz); MS (ESI) m/z 411 (M+H)+, 409 (M−H)−.

Provenance & Evidence