3-Fluoro-5-hydroxypyridine → Methyl 5-chloro-2-[(5-fluoropyridin-3-yl)oxy]benzoate

HRID 1293258Notes

Reaction equation

HRID 1293258 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5](F)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[F:13][C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[N:18][CH:19]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][C:16]2[CH:17]=[N:18][CH:19]=[C:14]([F:13])[CH:15]=2)=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8]

Participants

3

Reactant 2

HCID 27629063-Fluoro-5-hydroxypyridineHCID 21525433Methyl 5-chloro-2-fluorobenzoate

Product 1

HCID 69418031Methyl 5-chloro-2-[(5-fluoropyridin-3-yl)oxy]benzoate

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 5-chloro-2-fluorobenzoate and 5-fluoropyridin-3-ol: MS (ESI) m/z 282 (M+H)+.

Sources & evidence

ORD record
ord-0c326b71e180464e82bb358a58ced010
Source dataset
uspto-grants-2007_07
Patent number
US07238714B2

Reaction notes

Loading…