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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293258Generated: October 26, 2026

3-Fluoro-5-hydroxypyridine → Methyl 5-chloro-2-[(5-fluoropyridin-3-yl)oxy]benzoate

https://huagongshe.com/reaction/1293258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-5-hydroxypyridineHCID 2762906—
ReactantMethyl 5-chloro-2-fluorobenzoateHCID 21525433—
ProductMethyl 5-chloro-2-[(5-fluoropyridin-3-yl)oxy]benzoateHCID 69418031—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 5-chloro-2-fluorobenzoate and 5-fluoropyridin-3-ol: MS (ESI) m/z 282 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238714B2
Source datasetuspto-grants-2007_07
ORD IDord-0c326b71e180464e82bb358a58ced010
Source noteuspto-grants-2007_07