4-Chloro-2-fluorophenol → HCID 69418246, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 4-chloro-2-fluorophenol: 1H-NMR (CDCl3) δ 8.53 (1H, d, J=2.7 Hz), 8.10 (1H, d, J=2.7 Hz), 7.97–7.94 (3H, m), 7.42–7.39 (2H, m), 7.31–7.21 (3H, m), 5.37 (1H, quint, J=7.0 Hz), 1.61–1.58 (12H, m); MS (ESI) m/z 505 (M+H)+, 503 (M−H)−.

Provenance & Evidence