4-Fluoro-2-methylphenol → HCID 69418171, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from tert-butyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 45) and 4-fluoro-2-methylphenol: 1H-NMR (CDCl3) δ 8.57 (1H, d, J=2.6 Hz), 8.22 (1H, d, J=7.6 Hz), 8.11 (1H, d, J=2.6 Hz), 7.96 (2H, d, J=8.4 Hz), 7.41 (2H, d, J=8.4 Hz), 7.13–6.93 (3H, m), 5.39 (1H, dq, J=7.6, 6.9 Hz), 2.12 (3H, s), 1.60 (3H, d, J=6.9 Hz), 1.58 (9H, s); MS (ESI) m/z 485 (M+H)+, 483 (M−H)−.

Provenance & Evidence