2-Chloro-4-fluorophenol → HCID 69416999, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from methyl 4-((1S)-1-{[(2-chloro-5-fluoropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1) and 2-chloro-4-fluorophenol: 1H-NMR (CDCl3) δ 8.32 (1H, dd, J=8.1, 2.9 Hz), 8.19 (1H, d, J=7.3 Hz), 8.02–7.99 (3H, m), 7.45 (2H, d, J=8.3 Hz), 7.32–7.25 (2H, m), 7.14–7.08 (1H, m), 5.39 (1H, m), 3.90 (3H, s), 1.61 (3H, d, J=7.0 Hz).

Provenance & Evidence