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HRID1293320

反应详情

EQUATION

反应方程式

HRID 1293320 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc([C@H](C)N)cc1.Cl
HCID57462942

Methyl 4-[(1S)-1-aminoethyl]benzoate--hydrogen chloride (1/1)

C10H14ClNO2

结构：N#Cc1ccc(Oc2cccc(F)c2)c(C(=O)O)c1
HCID69418961

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc([C@H](C)NC(=O)c2cc(C#N)ccc2Oc2cccc(F)c2)cc1
HCID69419342

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 3 of Example 1 from 5-cyano-2-(3-fluorophenoxy)benzoic acid (step 1) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 5): 1H-NMR (CDCl3) δ 8.54 (1H, s), 7.97 (2H, d, J=8.4 Hz), 7.77–7.65 (2H, m), 7.47–7.34 (3H, m), 7.04–6.80 (4H, m), 5.35 (1H, m), 3.90 (3H, s), 1.54 (3H, d, J=7.8 Hz).