Morpholine → HCID 57091572, compound

HRID 129353Notes

Reaction equation

HRID 129353 reaction equation
Cl[CH2:2][CH2:3][CH2:4][S:5][C:6]1[CH:12]=[CH:11][C:9]([OH:10])=[CH:8][C:7]=1[OH:13].[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>>[O:17]1[CH2:18][CH2:19][N:14]([CH2:2][CH2:3][CH2:4][S:5][C:6]2[CH:12]=[CH:11][C:9]([OH:10])=[CH:8][C:7]=2[OH:13])[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 57192749HCID 57192749, compound

Product 1

HCID 57091572HCID 57091572, compound

Procedure

4 g of 4-(3-chloropropylthio)resorcin and 8 ml of morpholine are heated for two hours at 100° C. The mixture is poured into ice-cold water and extracted with ethyl acetate. The organic phases are washed, dried and concentrated under vacuum. The yellow oil is crystallized from ethyl acetate to lead to white crystals having a melting point of: 99° C.

Workup

  1. additionThe mixture is poured into ice-cold water
  2. extractionextracted with ethyl acetate
  3. washThe organic phases are washed
  4. customdried
  5. concentrationconcentrated under vacuum
  6. customThe yellow oil is crystallized from ethyl acetate

Sources & evidence

ORD record
ord-747efc1a7da74df8bde2a7878082bcbd
Source dataset
uspto-grants-1995_11
Patent number
US05468472

Reaction notes

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