Tert-Butylamine → 3-Bromo-N-tert-butylbenzene-1-sulfonamide

HRID 1293606Notes

Reaction equation

[C:1]([NH2:5])([CH3:4])([CH3:3])[CH3:2].[Br:6][C:7]1[CH:8]=[C:9]([S:13](Cl)(=[O:15])=[O:14])[CH:10]=[CH:11][CH:12]=1>>[Br:6][C:7]1[CH:8]=[C:9]([S:13]([NH:5][C:1]([CH3:4])([CH3:3])[CH3:2])(=[O:15])=[O:14])[CH:10]=[CH:11][CH:12]=1

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 17943m-Bromobenzenesulphonyl chloride

Product 1

HCID 48209263-Bromo-N-tert-butylbenzene-1-sulfonamideYield 106.4%

Procedure

Prepared by general procedure III from tert-butylamine (3.16 mL, 30 mmol) and commercially available 3-bromobenzenesulfonyl chloride (1.44 mL, 10 mmol) to give the title compound as a light yellow solid (3.11 g, 106%). MS (ISN) 290.1 [(M−H)−], 292.2 [(M+2−H)−].

Sources & evidence

ORD record: ord-c2f3c518f4564a8bbe519ad4bbb85cdb
Source dataset: uspto-grants-2007_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07238808B2

Reaction notes

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