Ethanol → 3-bromo-N-methylbenzene-1-sulfonamide

HRID 1293626Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.[CH3:12][NH2:13].CCO>>[Br:1][C:2]1[CH:3]=[C:4]([S:8]([NH:13][CH3:12])(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 3

HCID 702Ethanol

HCID 6329Methylamine

HCID 17943m-Bromobenzenesulphonyl chloride

Product 1

HCID 72132653-bromo-N-methylbenzene-1-sulfonamideYield 88%

Procedure

Prepared by general procedure III from 3-bromobenzenesulfonyl chloride (5.0 g, 20 mmol) and 2M solution of methylamine in EtOH (10.8 mL, 22 mmol) to give the title compound (4.3 g, 88%) as a white solid. MS (ISP) 250.0 [(M+H)+].

Sources & evidence

ORD record: ord-7d0257af5ca143b4a4b2c1099fceaa30
Source dataset: uspto-grants-2007_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07238808B2

Reaction notes

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