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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293725Generated: October 31, 2026

Trimethylsilylacetylene → HCID 67000874, compound

https://huagongshe.com/reaction/1293725

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantHCID 67000884HCID 67000884—
ProductHCID 67000874HCID 67000874—

Reaction Steps

Prepared from 8-cyclopropyl-3-iodo-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine (example C.25 step 5) (3.1 g, 7 mmol) and trimethylsilylacetylene (2.00 mL, 14 mmol) as described in example C.20 step 4. Obtained the title compound as an amorphous brown material (2.3 g, 79%). MS (ISP) 399.2 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238808B2
Source datasetuspto-grants-2007_07
ORD IDord-6b70e65de8744a7a9c8c2bc8bf33b49d
Source noteuspto-grants-2007_07