HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2(S)-(Piperidin-2-on-1-yl)-3-methylbutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2(S)-(piperidin-2-on-1-yl)-3-methylbutanoate | HCID 15283804 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2(S)-(Piperidin-2-on-1-yl)-3-methylbutanoic acid | HCID 15283805 | — |
Reaction Steps
The product of Step B was dissolved in 4 mL of methanol and 0.85 mL of 1N NaOH was added. The mixture was stirred overnight and the solvent was evaporated. The residue was dissolved in water, filtered and acidified. Ethyl acetate extraction and standard workup gave 30 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05468733 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-20674ea2b1934c38acbceef520a6098b |
| Source note | uspto-grants-1995_11 |