Sodium Hydroxide → HCID 58905711, compound

HRID 1294079Notes

Reaction equation

HRID 1294079 reaction equation
[CH2:1]([N:8]1[C:12]2[CH:13]=[C:14]([OH:17])[CH:15]=[CH:16][C:11]=2[N:10]=[C:9]1[NH2:18])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:19](C(OC(C)(C)C)=O)[C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=O.[OH-].[Na+]>N1C=CC=CC=1>[CH2:1]([N:8]1[C:12]2[CH:13]=[C:14]([OH:17])[CH:15]=[CH:16][C:11]=2[N:10]=[C:9]1[NH:18][C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:19])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 90495Di-tert-butyl dicarbonateHCID 69412160HCID 69412160, compound

Product 1

HCID 58905711HCID 58905711, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

1-Benzyl-6-hydroxy-2-amino-1H-benzimidazole was treated with BOC2O in pyridine, followed by hydrolysis with NaOH (aq) to give the title compound; MS m/e 340 (M+1).

Sources & evidence

ORD record
ord-d1cdd3513403483385cac67dd7a116e6
Source dataset
uspto-grants-2007_07
Patent number
US07238813B2

Reaction notes

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