反应详情

温度

100 °C

Fluoronitrobenzene (10.3 g, 0.073 mol) is dissolved in water and then potassium carbonate (12.1 g, 0.0876 mol) is added. 1-Methyl[1,4]diazepane (10 g, 0.0876 mol) is introduced and then the reaction medium is heated under reflux (≅100° C.) for 5 hours. The medium is cooled. A precipitate forms, which is filtered and washed with water. A yellow solid is recovered, which is dried at 45° C. in a vacuum oven (16.21 g, yield=94.5%).

1. temperaturethe reaction medium is heated
2. temperatureThe medium is cooled
3. filtrationA precipitate forms, which is filtered
4. washwashed with water
5. customA yellow solid is recovered
6. customwhich is dried at 45° C. in a vacuum oven (16.21 g, yield=94.5%)