2-Fluoro-6-methylpyridine → HCID 11472319, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:6][CH:7]=1.F[C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[N:18]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[N:18]=3)[CH:14]=2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
The title compound, MS: m/e=308.2 (M+H+), was prepared in accordance with the general method of example 1 from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2-fluoro-6-methyl-pyridine.
Sources & evidence
- ORD record
- ord-93a962acd13e4b009636110ef99de56f
- Source dataset
- uspto-grants-2007_07
- Patent number
- US07241760B2
Reaction notes
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