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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294502Generated: November 4, 2026

2-Chloro-4-methoxypyrimidine → 3-[1-(4-Methoxy-pyrimidin-2-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrile

https://huagongshe.com/reaction/1294502

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methoxypyrimidineHCID 588935—
ReactantHCID 178432699HCID 178432699—
Product3-[1-(4-Methoxy-pyrimidin-2-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrileHCID 11415791—

Reaction Steps

The title compound, MS: m/e=316.1 (M+H+), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 2-chloro-4-methoxypyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241760B2
Source datasetuspto-grants-2007_07
ORD IDord-f68e89358391451b9283ff795cd77616
Source noteuspto-grants-2007_07