Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | HCID 86601754 | HCID 86601754 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 58906421 | HCID 58906421 | — |
Reaction Steps
38.7 g (0.1 mol) N-(4-morpholin-4-yl-cyclohexyl)-4-nitro-3-prop-2-ynyloxy-benzamide are dissolved in 400 ml of ethyl acetate and 25 ml of methanol. To this solution are added 75 g tin (II)chloride.3H2O. The mixture is stirred for 16 h at 50° C. Then it is cooled to ambient temperature and 80 ml of conc. aqueous ammonia are added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07241769B2 |
|---|
| Source dataset | uspto-grants-2007_07 |
|---|
| ORD ID | ord-d2f0aa1807564e85957b403550354f9d |
|---|
| Source note | uspto-grants-2007_07 |
|---|
