Methylamine → 20431-81-6

HRID 1294583Notes

Reaction equation

HRID 1294583 reaction equation
[CH:1]12[O:7][CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6]2.[CH3:8][NH2:9]>>[CH3:8][NH:9][CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[OH:7]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 9246Cyclohexene oxide

Product 1

HCID 31673120431-81-6

Conditions

Temperature
40 °C

Procedure

Cyclohexene oxide (147 g, 1.5 mol) was dissolved in a ethanolic 8 M methylamine solution (750 ml) and stirred at 40° C. for 16 h. The reaction mixture was concentrated in vacuo to give racemic 2-methylaminocyclohexanol as a slightly brown oil (195 g, 100%). According to GC-analysis this product was 99+% pure and used without further purification.

Workup

  1. concentrationThe reaction mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-85c615fea1a341b882769cfcf49a1ec0
Source dataset
uspto-grants-2007_07
Patent number
US07241770B2

Reaction notes

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