HCID 86093123, compound → 1-[2-(morpholin-4-yl)phenyl]ethan-1-amine

Participants

Reaction Steps

A mixture of Example 49B (1.3 g, 5.54 mmol) and Raney nickel (14 g) in a mixture of 20% NH3 in methanol (140 mL) was hydrogenated at 60 psi for 11 hrs. The reaction was filtered and concentrated to dryness under reduced pressure to give 1.1 g of the title compound. MS (ESI+) m/z 207 (M+H)+.

Provenance & Evidence