2-Hydroxy-1-naphthaldehyde → HCID 136380447, compound

HRID 1294722Notes

Reaction equation

[S:1]([C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:12](=[S:15])[NH:13][NH2:14])=[CH:7][CH:6]=1)([OH:4])(=[O:3])=[O:2].[Na].[OH:17][C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:19]=1[CH:28]=O>>[OH:17][C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:19]=1[CH:28]=[N:14][NH:13][C:12]([NH:11][C:8]1[CH:7]=[CH:6][C:5]([S:1]([OH:4])(=[O:2])=[O:3])=[CH:10][CH:9]=1)=[S:15]

Participants

Reactant 3

HCID 128192-Hydroxy-1-naphthaldehyde

HCID 5360545Sodium

HCID 11053969HCID 11053969, compound

Product 1

HCID 136380447HCID 136380447, compoundYield 23%

Procedure

The procedure described in example 4 was followed here, using 4-(4-sulfophenyl)-3-thiosemicarbazide, sodium salt in place of 4-(naphth-1-yl)thiosemicarbazide and 2-hydroxy-1-naphthaldehyde in place of 2,4,6-trihydroxybenzaldehyde to give the title compound (23%) as a solid. MS (ES−) m/e 400 [M−H]−.

Sources & evidence

ORD record: ord-ae3a96e3451a4ad486dac9ff90b66387
Source dataset: uspto-grants-2007_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07241783B2

Reaction notes

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