HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 10392326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-(Pyridin-3-yl)benzaldehyde | HCID 3693046 | — |
| Reactant | HCID 11590834 | HCID 11590834 | — |
| Reactant | HCID 178419135 | HCID 178419135 | — |
| Product | HCID 10392326 | HCID 10392326 | 113.3% |
Reaction Steps
Using the same method as for COMPOUND 17 and using INTERMEDIATE 5a (205 mg, 0.44 mmol), 4-(3-pyridinyl)benzaldehyde (88.7 mg, 0.48 mmol), and decaborane (16.4 mg, 0.13 mmol) afforded COMPOUND 52 (266 mg, 61% yield) as its TFA salt. This material was lyophilized from CH3CN/H2O to produce a slightly yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241764B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-61407ac0d4724b6e936ac46ea9f803fc |
| Source note | uspto-grants-2007_07 |