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HRID1294807

反应详情

EQUATION

反应方程式

HRID 1294807 的结构方程式

REACTANTS

反应物

3
结构：CCOC(C)=O
HCID8857

Ethyl acetate

C4H8O2

结构：Cl.c1ccc2c(N3CCNCC3)nsc2c1
HCID11521711

3-(1-Piperazinyl)-1,2-benzisothiazole monohydrochloride

C11H14ClN3S

结构：C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)O)C(F)(F)F
HCID58863351

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nsc3ccccc23)CC1)C(F)(F)F
HCID11577135

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Prepared in analogy to example 1.1 b) from 5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-benzoic acid (Example 2.7) and 3-piperazin-1-yl-benzo[d]isothiazole hydrochloride (CA=87691-88-1) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a colorless solid.