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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294859Generated: October 30, 2026

Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)- → (2-Fluoro-3-trifluoromethyl-phenyl)-(4-methoxy-phenyl)-methanone

https://huagongshe.com/reaction/1294859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-HCID 11196047—
ReactantHCID 178491912HCID 178491912—
Product(2-Fluoro-3-trifluoromethyl-phenyl)-(4-methoxy-phenyl)-methanoneHCID 11231817—

Reaction Steps

Prepared according to Method A step B from 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)benzamide (2.5 g, 10 mmol) and 4-methoxyphenylmagnesium bromide (20 mL, 0.5 M in THF) to give 2.1 g of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241791B2
Source datasetuspto-grants-2007_07
ORD IDord-5ecc7334745b4779ab621cb927907630
Source noteuspto-grants-2007_07