HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)- → [2-Fluoro-3-(trifluoromethyl)phenyl](4-methoxy-2-methylphenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)- | HCID 11196047 | — |
| Reactant | HCID 178491917 | HCID 178491917 | — |
| Product | [2-Fluoro-3-(trifluoromethyl)phenyl](4-methoxy-2-methylphenyl)methanone | HCID 67021619 | — |
Reaction Steps
Prepared according to Method A step B from 2- fluoro-3-trifluoromethyl-N-methoxy-N-methylbenzamide (4.05 g, 16.1 mmol) and 2-methyl-4-methoxyphenylmagnesium bromide (42 mL, 0.5 M in THF) to give 1.76 g of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-d95fa1a4f79f44289d6c4203c9102582 |
| Source note | uspto-grants-2007_07 |