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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294872Generated: October 26, 2026

3-chloro-2-fluoro-N-methoxy-N-methylbenzamide → (3-Chloro-2-fluorophenyl)(2,4-dimethoxyphenyl)methanone

https://huagongshe.com/reaction/1294872

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-chloro-2-fluoro-N-methoxy-N-methylbenzamideHCID 11470003—
ReactantHCID 178491918HCID 178491918—
Product(3-Chloro-2-fluorophenyl)(2,4-dimethoxyphenyl)methanoneHCID 64713965—

Reaction Steps

Prepared according to Method A step B from 2-fluoro-3-chloro-N-methoxy-N-methyl-benzamide (2.44 g, 11.2 mmol) and 2,4-dimethoxyphenylmagnesium bromide (20 mL, 0.5 M in THF) to give 0.95 g of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241791B2
Source datasetuspto-grants-2007_07
ORD IDord-4c3f0f417fa6450e924c4307967767aa
Source noteuspto-grants-2007_07