HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylhydrazine hydrochloride → 7-chloro-1-cyclohexyl-3-(4-methoxyphenyl)-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylhydrazine hydrochloride | HCID 207836 | — |
| Reactant | (3-Chloro-2-fluorophenyl)-(4-methoxyphenyl)-methanone | HCID 11471075 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | 7-chloro-1-cyclohexyl-3-(4-methoxyphenyl)-1H-indazole | HCID 68885462 | 92% |
Reaction Steps
Prepared according to Method C step A (3-chloro-2-fluorophenyl)-(4-methoxyphenyl)-methanone (0.55 g, 1.85 mmol), cyclohexylhydrazine hydrochloride (0.42 g, 2.7 mmol) and DMAP (0.225 g, 1.85 mmol) to give the product (0.58 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-a4e98cefb01d48c187200ffea1e41cdf |
| Source note | uspto-grants-2007_07 |