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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294902Generated: October 29, 2026

Cyclohexene → 4-[1-cyclohexyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenol

https://huagongshe.com/reaction/1294902

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexeneHCID 8079—
ReactantBoron tribromideHCID 25134—
Reactant1-cyclohexyl-3-(4-methoxyphenyl)-7-trifluoromethyl-1H-indazoleHCID 68882046—
Product4-[1-cyclohexyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenolHCID 13546559515.5%

Reaction Steps

Prepared according to Method C step B from 1-cyclohexyl-3-(4-methoxyphenyl)-7-trifluoromethyl-1H-indazole (0.5 mmol), boron tribromide (0.188 mL, 2.0 mmol) and 0.2 mL of cyclohexene to give the product (0.028 g) as a tan solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241791B2
Source datasetuspto-grants-2007_07
ORD IDord-aa37159a7b774b27a1fd6af561e543b4
Source noteuspto-grants-2007_07