HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 7-chloro-3-(4-methoxyphenyl)-1-(3,3,3-trifluoropropyl)-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1,1,1-Trifluoro-3-iodopropane | HCID 156165 | — |
| Reactant | HCID 178489137 | HCID 178489137 | — |
| Product | 7-chloro-3-(4-methoxyphenyl)-1-(3,3,3-trifluoropropyl)-1H-indazole | HCID 68886144 | 5.6% |
Reaction Steps
Prepared according to Method D step B from 7-chloro-3-(4-methoxyphenyl)-1H-indazole (0.108 g, 0.4 mmol), sodium hydride (60% in oil, 0.016 g, 0.4 mmol) and 3,3,3-trifluoropropyliodide (0.047 mL, 0.4 mmol) to give the title compound (0.008 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-80155674fff948c4af8a2a52883bc3fa |
| Source note | uspto-grants-2007_07 |