HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-chloro-2-fluoro-N-methoxy-N-methylbenzamide → (3-Chloro-2-fluorophenyl)(3-fluoro-4-methoxyphenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-chloro-2-fluoro-N-methoxy-N-methylbenzamide | HCID 11470003 | — |
| Reactant | HCID 178491915 | HCID 178491915 | — |
| Product | (3-Chloro-2-fluorophenyl)(3-fluoro-4-methoxyphenyl)methanone | HCID 64712239 | — |
Reaction Steps
Prepared according to Method A step B from 3-chloro-2-fluoro-N-methoxy-N-methylbenzamide (4.0 g, 18.4 mmol) and bromo(3-fluoro-4-methoxyphenyl)magnesium (100 mL, 2M in diethyl ether). The title compound was obtained as a white solid (1.65 g, 5.85 mmol, 32%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-c32623d42b134da6a698b372b2819a7c |
| Source note | uspto-grants-2007_07 |