反应详情

A mixture of ethyl (E)-3-(3-benzyloxy-1-phenyl-1H-pyrazol-4-yl)propenoate (2.70 g), 5% palladium-carbon (3.00 g) and tetrahydrofuran (100 ml) was stirred under a hydrogen atmosphere at room temperature for 3 hrs. Palladium-carbon was filtered off and the filtrate was concentrated. The obtained crystals were collected by filtration to give ethyl 3-(3-benzyloxy-1-phenyl-1H-pyrazol-4-yl)propionate (1.78 g, yield 89%), which was then recrystallized from ethyl acetate-hexane. melting point: 123–124° C.

1. filtrationPalladium-carbon was filtered off
2. concentrationthe filtrate was concentrated
3. filtrationThe obtained crystals were collected by filtration