HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl]-3-(2-hydroxy-1-hydroxymethylethyl)urea → 1-[3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl]-3-(2-hydroxy-1-hydroxymethylethyl)urea hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl]-3-(2-hydroxy-1-hydroxymethylethyl)urea | HCID 11384708 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 1-[3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl]-3-(2-hydroxy-1-hydroxymethylethyl)urea hydrochloride | HCID 69511909 | 178.6% |
Reaction Steps
200 mg of 1-[3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl]-3-(2-hydroxy-1-hydroxymethylethyl)urea (Example compound 6) were dissolved in 40 ml of 0.1 M HCl, filtered and freeze-dried to obtain 194 mg of the desired hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241775B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-3bd28a78fa1946c9abcc9023f79cc323 |
| Source note | uspto-grants-2007_07 |