HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methoxyphenyl)acetic acid → 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methoxyphenyl)acetic acid | HCID 15719 | — |
| Reactant | tetra-Aminopyrimidine | HCID 70487 | — |
| Reactant | 4,5,6-Pyrimidinetriamine, sulfate (1:1) | HCID 111544 | — |
| Reactant | 2-(2-Methoxyphenyl)acetyl chloride | HCID 179502 | — |
| Reactant | 2-fluoro-7H-purine | HCID 4323424 | — |
| Product | 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine | HCID 5289228 | — |
| Product | 9-Butyl-8-(2-methoxy-benzyl)-9H-purin-6-ylamine | HCID 67230252 | — |
Reaction Steps
9-Butyl-8-(2-methoxy-benzyl)-9H-purin-6-ylamine and 9-butyl-8-(3-methoxy-benzyl)-9H-purin-6-ylamine were prepared from 4,5,6-triaminopyrimidine sulfate and, respectively 2-methoxyphenyl acetyl chloride or 3-methoxyphenyl acetic acid, by procedures analogous to the one described above. 2-Fluoro purine analogs were also prepared from 2,4,5,6-tetraaminopyrimidine, by procedures analogous to those described above. See Example 2, step 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241890B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-8586363e89944167952c27c8c0fa2c50 |
| Source note | uspto-grants-2007_07 |