HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-butylindole-3-carboxylic Acid → 1-butyl-2-{2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-yl(hydroxy)methyl}-1H-indole-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-butylindole-3-carboxylic Acid | HCID 10376290 | — |
| Reactant | HCID 15225578 | HCID 15225578 | — |
| Product | 1-butyl-2-{2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-yl(hydroxy)methyl}-1H-indole-3-carboxylic acid | HCID 19371907 | — |
Reaction Steps
reacting the 2-lithiated 1-butyl-1H-indole-3-carboxylic acid with protected 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carbaldehyde to give 1-butyl-2-{2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-yl(hydroxy)methyl}-1H-indole-3-carboxylic acid;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05468867 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-ed105e98f4694dc2b9f27d917f14e861 |
| Source note | uspto-grants-1995_11 |