HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1295731Generated: October 31, 2026
Methylamine → 3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-benzylidene-methyl-amine
https://huagongshe.com/reaction/1295731
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 3-(2-{[tert-Butyl(dimethyl)silyl]oxy}ethoxy)benzaldehyde | HCID 71417113 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-benzylidene-methyl-amine | HCID 69508322 | 87.89% |
Reaction Steps
3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-benzaldehyde (2.375 g, 8.47 mmol) was dissolved in 10 mL EtOH. MeNH2 (1.2 mL, 40% in H2O) was added and the mixture was heated to 40° C. for 30 min. The mixture was then concentrated in vacuo. The aqueous residue was diluted with isopropanol and then concentrated in vacuo. This was repeated twice more giving 2.184 g (87.89%) of a dry white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07244738B2 |
|---|
| Source dataset | uspto-grants-2007_07 |
|---|
| ORD ID | ord-cfa152d5c85340b7876cd666a0f794b6 |
|---|
| Source note | uspto-grants-2007_07 |
|---|
