Methylamine → 828242-89-3

HRID 1295736Notes

Reaction equation

HRID 1295736 reaction equation
[CH3:1][S:2][CH2:3][O:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[CH:8]=O.[CH3:13][NH2:14]>CCO>[CH3:13][N:14]=[CH:8][C:7]1[CH:10]=[CH:11][CH:12]=[C:5]([O:4][CH2:3][S:2][CH3:1])[CH:6]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 714171123-[(Methylsulfanyl)methoxy]benzaldehyde

Product 1

HCID 69507905828242-89-3

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
40 °C

Procedure

3-Methylsulfanylmethoxy-benzaldehyde from step 1 (3.309 g, 18.16 mmol) was dissolved in EtOH (9 mL). MeNH2 (2.55 mL, 40% in H2O) was added and the mixture was heated to 40° C. for 30 min. Upon cooling, the mixture was concentrated in vacuo. The aqueous residue was diluted with isopropanol and then concentrated in vacuo. This was repeated twice more giving 3.55 g (quant) of a pale yellow oil.

Workup

  1. temperatureUpon cooling
  2. concentrationthe mixture was concentrated in vacuo
  3. additionThe aqueous residue was diluted with isopropanol
  4. concentrationconcentrated in vacuo
  5. customThis was repeated twice more giving 3.55 g (quant) of a pale yellow oil

Sources & evidence

ORD record
ord-1d7ba7712bc54ebab51e00a99045115a
Source dataset
uspto-grants-2007_07
Patent number
US07244738B2

Reaction notes

Loading…